A Clinical Trial to Evaluate the Effectiveness Lactobacillus Reuteri for Treatment of Chronic Periodontitis

2019-10-23 13:11:55 | BioPortfolio


The aim of this study is to determine the efficacy of the subgingival application of probiotic oil drops on microbial shift and clinical improvement after periodontal non-surgical treatment.

Study Design






Not yet recruiting


Second Affiliated Hospital, School of Medicine, Zhejiang University

Results (where available)

View Results


Published on BioPortfolio: 2019-10-23T13:11:55-0400

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Medical and Biotech [MESH] Definitions

Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)

Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.

Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.

Live microbial DIETARY SUPPLEMENTS which beneficially affect the host animal by improving its intestinal microbial balance. Antibiotics and other related compounds are not included in this definition. In humans, lactobacilli are commonly used as probiotics, either as single species or in mixed culture with other bacteria. Other genera that have been used are bifidobacteria and streptococci. (J. Nutr. 1995;125:1401-12)

A species of gram-positive, rod-shaped bacteria used in PROBIOTICS.

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