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HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

2019-10-24 12:49:52 | BioPortfolio

Summary

The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III that is human papillomavirus (HPV) 16+.

Study Design

Conditions

Human Papillomavirus Type 16

Intervention

pNGVL4aCRTE6E7L2

Location

Johns Hopkins University
Baltimore
Maryland
United States
21231

Status

Not yet recruiting

Source

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-24T12:49:52-0400

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A type of ALPHAPAPILLOMAVIRUS associated with high risk for anogenital neoplasms.

A type of ALPHAPAPILLOMAVIRUS usually associated with GENITAL WARTS; and LARYNGEAL NEOPLASMS.

A type of ALPHAPAPILLOMAVIRUS especially associated with malignant tumors of the CERVIX and the RESPIRATORY MUCOSA.

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