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Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC)

2019-10-24 12:49:22 | BioPortfolio

Summary

This is a randomized, double-blind, placebo controlled multicenter study.

A total of 700 patients will be included.

The study will include patients with primary sclerosing cholangitis (PSC) for daily intake of 40 mg simvastatin/placebo for 5 years. The aim is to study effect of prognosis of PSC by long term intake of simvastatin. Outcome measures are death, liver transplantation, cholangiocarcinoma or bleeding from esophageal varices.

Subjects will be randomized (1:1) between Simvastatin and placebo.

Study Design

Conditions

Primary Sclerosing Cholangitis

Intervention

Simvastatin 40mg, Placebo oral tablet

Status

Not yet recruiting

Source

Karolinska University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-24T12:49:22-0400

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