Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP0678, and the Effect of Food on ZSP0678 Pharmacokinetics

2019-10-28 13:56:50 | BioPortfolio


This study will evaluate the safety, tolerability and pharmacokinetics (PK) of escalating single-and multiple-oral doses of ZSP0678 on fasted condition, and characterize PK of ZSP0678 on an empty stomach (fasted condition) and following a high fat, high calorie meal (fed condition) in a 2-period, 2-sequence manner. The study will be conducted in 3 parts (Ascending single dose, multiple dose and food effect). Participants will receive either ZSP0678 or placebo .

Study Design


Nonalcoholic Steatohepatitis


ZSP0678-10mg, ZSP0678-30mg, ZSP0678-60mg, ZSP0678-120mg, ZSP0678-180mg, ZSP0678-240mg, ZSP0678-320mg, ZSP0678, ZSP0678-Dose 1, ZSP0678-Dose 2, ZSP0678-Dose 3, ZSP0678 Placebo


Beijing Friendship Hospital Affiliated to Capital Medical Universit


Not yet recruiting


Guangdong Raynovent Biotech Co., Ltd

Results (where available)

View Results


Published on BioPortfolio: 2019-10-28T13:56:50-0400

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