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Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP0678, and the Effect of Food on ZSP0678 Pharmacokinetics

2019-10-28 13:56:50 | BioPortfolio

Summary

This study will evaluate the safety, tolerability and pharmacokinetics (PK) of escalating single-and multiple-oral doses of ZSP0678 on fasted condition, and characterize PK of ZSP0678 on an empty stomach (fasted condition) and following a high fat, high calorie meal (fed condition) in a 2-period, 2-sequence manner. The study will be conducted in 3 parts (Ascending single dose, multiple dose and food effect). Participants will receive either ZSP0678 or placebo .

Study Design

Conditions

Nonalcoholic Steatohepatitis

Intervention

ZSP0678-10mg, ZSP0678-30mg, ZSP0678-60mg, ZSP0678-120mg, ZSP0678-180mg, ZSP0678-240mg, ZSP0678-320mg, ZSP0678, ZSP0678-Dose 1, ZSP0678-Dose 2, ZSP0678-Dose 3, ZSP0678 Placebo

Location

Beijing Friendship Hospital Affiliated to Capital Medical Universit
Beijing
China
100050

Status

Not yet recruiting

Source

Guangdong Raynovent Biotech Co., Ltd

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-28T13:56:50-0400

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