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Drug-coated Balloon for Takayasu Arteritis Associated Renal Artery Stenosis

2019-10-29 14:36:48 | BioPortfolio

Summary

Takayasu arteritis associated renal artery stenosis (TARAS) is the biggest cause of hypertension in young people <40 years old. Hypertension caused by renal artery stenosis is usually hard to control in spite of two or more anti-hypertension drugs.

Percutaneous transluminal angioplasty (PTA) is recommended for hypertension caused by TARAS. In previous clinical practice, we observed relatively effects of PTA on controlling the blood pressure in patients with TARAS. But, high re-stenosis rate was also indicated. Drug coated balloon (DCB)is a new type of PTA, which could improve the re-stenosis rate significantly. In the clinical trials of peripheral vascular disease, it has been confirmed that DCB had lower re-stenosis rate than PTA. However, up to date, no studies was found about the use of DBC in TARAS.

Thus, this study was design as a random, double blind trial to evaluated the effects and safety of DCB in the treatment of hypertension caused by TARAS.

Study Design

Conditions

Takayasu Arteritis

Intervention

Drug coated balloon (DCB), Digital substraction angiography (DSA)

Location

ZhongshanHospital
Shanghai
Shanghai
China
200032

Status

Not yet recruiting

Source

Shanghai Zhongshan Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-29T14:36:48-0400

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Medical and Biotech [MESH] Definitions

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