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Transcriptomic Evaluation of Endometrial Receptivity

2019-10-31 14:29:40 | BioPortfolio

Summary

The purpose of this study is to comprehensively evaluate the transcriptomic signal of the endometrium before, during, and after the window of receptivity.

Description

Phase 1 will aim to define a normal endometrial transcriptomic signature in healthy controls without infertility. Phase 2 will elucidate endometrial transcriptomic expression in patients with diagnoses of infertility unrelated to endometrial factor. Findings from this phase will be compared to the results of phase 1.

Study Design

Conditions

Infertility, Female

Intervention

Endometrial biopsy

Location

Reproductive Medicine Assoicates of New Jersey
Basking Ridge
New Jersey
United States
07920

Status

Recruiting

Source

Reproductive Medicine Associates of New Jersey

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-31T14:29:40-0400

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Medical and Biotech [MESH] Definitions

Diminished or absent ability of a female to achieve conception.

Neoplasms of the endometrial stroma that sometimes involve the MYOMETRIUM. These tumors contain cells that may closely or remotely resemble the normal stromal cells. Endometrial stromal neoplasms are divided into three categories: (1) benign stromal nodules; (2) low-grade stromal sarcoma, or endolymphatic stromal myosis; and (3) malignant endometrial stromal sarcoma (SARCOMA, ENDOMETRIAL STROMAL).

Conducting a biopsy procedure with the aid of a MEDICAL IMAGING modality.

The extension of endometrial tissue (ENDOMETRIUM) into the MYOMETRIUM. It usually occurs in women in their reproductive years and may result in a diffusely enlarged uterus with ectopic and benign endometrial glands and stroma.

Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.

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