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Addition of Anlotinib Hydrochloride to the Stupp Regimen Versus the Stupp Regimen Alone for Newly Diagnosed Glioblastoma

2019-11-14 17:39:52 | BioPortfolio

Summary

For patients with glioblastoma,postoperative radiotherapy combined with concurrent and adjuvant temozolomide (Stupp regimen) has long been considered a standard treatment approach.The treatment outcomes, however, are still dismal, with a median overall survival time of 8-12 months. As a novel small molecule multi-target tyrosine kinase inhibitor, anlotinib hydrochloride has been found to be able to inhibit both tumor angiogenesis and cell growth.Previous studies on recurrent glioblastoma have demonstrated its effectiveness in tumor control with manageable toxicities. The current study is designed to evaluate the efficacy and feasibility of the additional anlotinib hydrochloride to the Stupp regimen for newly diagnosed glioblastoma.

Study Design

Conditions

Glioblastoma

Intervention

Anlotinib Hydrochloride, Radiation therapy, Temozolomide

Location

Nanxishan Hospital of Guangxi Zhuang Autonomous Region
Guilin
Guangxi
China
541002

Status

Not yet recruiting

Source

People's Hospital of Guangxi

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-11-14T17:39:52-0500

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