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Expanded Access Program Using Uromune for Patients With Recurrent Urinary Tract Infections (rUTI)

2019-11-26 22:07:40 | BioPortfolio

Summary

An Expanded Access Program for UROMUNE® for patients suffering from recurrent/chronic urinary tract infections of diverse etiology. This is for individuals for whom antibiotic therapy has failed, but of consideration in all cases, taking into account antibiotic-induced adverse reactions and increasing antibiotic resistance.

Description

UROMUNE® is a mucosal immunotherapy indicated for the prevention of urinary tract infections caused by different pathogens. It works by stimulating the immune system, thus increasing the resistance against recurrent infections. The active substances are 4 inactivated and selected bacterial strains:

- Klebsiella pneumoniae 25%

- Escherichia coli 25%

- Enterococcus faecalis 25%

- Proteus vulgaris 25%

Study Design

Conditions

Urinary Tract Infections

Intervention

Uromune

Location

Belgium
Brussels
Belgium

Status

Temporarily not available

Source

Impatients N.V. trading as myTomorrows

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-11-26T22:07:40-0500

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PubMed Articles [5799 Associated PubMed Articles listed on BioPortfolio]

Active immunoprophyilaxis with uromune® decreases the recurrence of urinary tract infections at three and six months after treatment without relevant secondary effects.

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Catheter-Associated Urinary Tract Infections in Adults: Diagnosis, Treatment, and Prevention.

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Medical and Biotech [MESH] Definitions

Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.

A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.

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Symptoms of disorders of the lower urinary tract including frequency, NOCTURIA; urgency, incomplete voiding, and URINARY INCONTINENCE. They are often associated with OVERACTIVE BLADDER; URINARY INCOMPETENCE; and INTERSTITIAL CYSTITIS. Lower urinary tract symptoms in males were traditionally called PROSTATISM.

Strains of Escherichia coli that preferentially grow and persist within the urinary tract. They exhibit certain virulence factors and strategies that cause urinary tract infections.

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