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Simvastatin in Uveitis

2019-12-06 00:24:49 | BioPortfolio

Summary

The study evaluates anti-inflammatory effects and safety of simvastatin in non-infectious uveitis.

Description

3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors (statins) have been shown to reduce local and systemic inflammation in animal models of various autoimmune disorders including uveitis. In this open-label, randomized study clinical efficacy and tolerability of simvastatin 40 mg/day for 8 weeks is evaluated.

Study Design

Conditions

Uveitis

Intervention

Simvastatin 40mg

Location

Laboratory of Clinical Immunopharmacology
Novosibirsk
Russian Federation
630047

Status

Completed

Source

Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-12-06T00:24:49-0500

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Medical and Biotech [MESH] Definitions

A pharmaceutical preparation of ezetimibe and simvastatin that is used in the treatment of HYPERCHOLESTEROLEMIA and HYPERLIPIDEMIAS.

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