Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.

2019-12-08 01:41:37 | BioPortfolio


Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.


Neurotensin (NT), a gut hormone and neuropeptide, and GLP-1, as well a gut hormone, increases in circulation after bariatric surgery in rodents and humans and inhibit food intake in mice.

Studies in rodents have shown that a GLP-1 receptor agonist and long acting neurotensin inhibit food intake.

This study investigates whether the synergistic anorexic effects of neurotensin and GLP-1 agonism suggested by animal studies can be translated.

Study Design




Saline + saline, Neurotensin + saline, GLP-1 + saline, GLP-1 + Neurotensin


University of Copenhagen, Department of Biomedical Scienses




University of Copenhagen

Results (where available)

View Results


Published on BioPortfolio: 2019-12-08T01:41:37-0500

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Medical and Biotech [MESH] Definitions

A genus of HALOBACTERIACEAE distinguished from other genera in the family by the presence of specific derivatives of TGD-2 polar lipids. Haloarcula are found in neutral saline environments such as salt lakes, marine salterns, and saline soils.

A family of gram-negative, moderately halophilic bacteria in the order Oceanospirillales. Members of the family have been isolated from temperate and Antarctic saline lakes, solar salt facilities, saline soils, and marine environments.

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A species of PERCIFORMES commonly used in saline aquaculture.

Water from natural sources which contain significant concentrations of dissolved salts such as sodium chloride.

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