Molecular Genetics Studies of Cancer Patients and Their Relatives

2019-12-06 00:24:27 | BioPortfolio


This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.



I. To identify rare cancer patients and families in whom the pattern of disease suggests a genetic susceptibility to cancer or other etiology suggestive of a carcinogenic exposure and to characterize the underlying predisposition.

II. To determine the contribution of heredity (genotype) and biomarkers to clinical outcome (phenotype, occurrence of new cancers, prognosis and quality of life) in subgroups of cancer patients with and without clinical high-risk features.


Patients may provide a sample of blood, a saliva sample, a sample of eyebrow plucks, a sample of urine, and/or stored tumor or healthy tissue.

Study Design


Malignant Neoplasm


Biospecimen Collection, Questionnaire Administration


Valleywise Comprehensive Health Center - Phoenix
United States




City of Hope Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2019-12-06T00:24:27-0500

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