Butyrophilins Role in Colon Cancer

2019-12-10 01:21:17 | BioPortfolio


quantification of BTN and BTNL molecules in colon cancer in order to determinate if their could be used as a prognostic marquer

Study Design


Colonic Cancer


analysis of BTN and BTNL status


Not yet recruiting


Institut Paoli-Calmettes

Results (where available)

View Results


Published on BioPortfolio: 2019-12-10T01:21:17-0500

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Medical and Biotech [MESH] Definitions

Tumors or cancer of the COLON.

Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.

A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.

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Colon or Colorectal cancer is the growth of malignant polyps on the colon, bowel, anus and rectum. Growths in these locations can be benign, and removed by colonoscopy, but they have a risk of becoming malignant.  About 10 per cent of bowel cancer...

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