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Combining Left Atrial Appendage Closure With Cryoballoon Ablation in Chinese Population

2019-12-10 01:21:19 | BioPortfolio

Summary

Cryoablation combined with left atrial appendage closure is a novel strategy for atrial fibrillation patients. Through long-term follow-up, the investigators aimed to observe the safety and efficacy of the combined procedure in Chinese population.

Description

the investigators aimed to observe the clinical outcome of combining cryoballoon ablation (CBA) with left atrial appendage closure (LAAC) in drug-refractory non-valvular atrial fibrillation patients, who have high risk of stroke or hemorrhage, or contraindication of long-term oral anticoagulants (OACs).

The combined procedure was completed using CBA following LAAC. Generally, 3-month OACs, following 3-month double antiplatelet therapy, and lifelong single platelet therapy was recommended as antithrombotic regimen.

At 3rd,6th,12th and every year after since the procedure, Holter and transoesophageal echocardiography monitoring, and outpatient follow-up was applied to every patient.

The safety was evaluated by all-cause mortality, peri- and postprocedural complications. While the efficacy was evaluated through the freedom of atrial arrhythmia, stroke incidence, and withdrawal of OACs.

Study Design

Conditions

Atrial Fibrillation

Intervention

cryoballoon ablation combining with left atrial appendage closure

Location

Department of Cardiology, Shanghai Tenth People's Hospital
Shanghai
Shanghai
China
200072

Status

Recruiting

Source

Shanghai 10th People's Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-12-10T01:21:19-0500

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Medical and Biotech [MESH] Definitions

Ear-shaped appendage of either atrium of the heart. (Dorland, 28th ed)

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