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Compare the Skin Barrier Repair Function of Two Ceramide Containing Moisturizers

2019-12-08 01:41:44 | BioPortfolio

Summary

This study aims to evaluate the improvement of CeraVe moisturising lotion on the cuticle moisture of dry skin and barrier repair function.

Study Design

Conditions

CeraVe Moisturising Lotion

Intervention

Ceramides

Location

Peking University First Hospital
Beijing
China

Status

Recruiting

Source

Peking University First Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-12-08T01:41:44-0500

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PubMed Articles [48 Associated PubMed Articles listed on BioPortfolio]

Elevated serum ceramides are linked with obesity-associated gut dysbiosis and impaired glucose metabolism.

Low gut microbiome richness is associated with dyslipidemia and insulin resistance, and ceramides and other sphingolipids are implicated in the development of diabetes.

Associations between specific plasma ceramides and severity of coronary-artery stenosis assessed by coronary angiography.

Recent prospective studies have identified distinct plasma ceramides as strong predictors of major adverse cardiovascular events in patients with established or suspected coronary artery disease (CAD)...

Roles of Ceramides and Other Sphingolipids in Immune Cell Function and Inflammation.

Ceramides are bioactive sphingolipids that support the structure of the plasma membrane and mediate numerous cell-signaling events in eukaryotic cells. The finding that ceramides act as second messeng...

Selectivity in cornified envelop binding of ceramides in human skin and the role of LXR inactivation on ceramide binding.

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Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain.

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Medical and Biotech [MESH] Definitions

A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

Amidohydrolases that are specific for the cleavage of the N-acyl linkage of CERAMIDES. Ceramidases are classified as acidic, neutral or basic according to the optimal pH with which they function.

Any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol (see GLYCERIDES), a sphingoid, a ceramide (CERAMIDES) (N-acylsphingoid) or a prenyl phosphate. (From IUPAC's webpage)

A group of MYCOTOXINS found in CORN contaminated with FUSARIUM fungus. They are chains of about 20 carbons with acidic ester, acetylamino and sometimes other substituents. They inhibit ceramide synthetase conversion of SPHINGOLIPIDS to CERAMIDES.

Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.

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