Hybrid Pump Technology

2020-01-22 12:12:52 | BioPortfolio


Prostheses can be suspended from the amputated limb using a variety of techniques, such as straps and suction. Suspending the prosthesis by creating a vacuum between the prosthetic socket and limb using a pump has benefits over other techniques including improved limb health and mobility. A new pump design will be tested by prosthesis users in the laboratory to verify its functionality during walking.


Human subject testing will involve a cross-sectional, repeated measures study consisting of a single 3 hour visit wherein participants will initially stand and then continuously walk at their self-selected speed for ten minutes on a level treadmill with the prototype under two randomly presented conditions of the mechanical system: 1) fully functional, and 2) locked to restrict axial displacement. After written informed consent is obtained, information on socket comfort and mobility capability will be collected. A load-cell will be installed proximal to the prototype and in-line with the prosthesis to measure instantaneous socket-reaction moments.

Study Design




Pump prototype


Jesse Brown VA Medical Center, Chicago, IL
United States


Not yet recruiting


VA Office of Research and Development

Results (where available)

View Results


Published on BioPortfolio: 2020-01-22T12:12:52-0500

Clinical Trials [663 Associated Clinical Trials listed on BioPortfolio]

Evaluation of Fluid-Filled Expression Core Technology Study - I

A functional model of a fluid-filled, smaller dead volume breast pump has been developed in order to more closely mimic the breastfeeding infant. The technology of fluid-filled pumping has...

Testing Self-regulation Effects of a `Smart Toy'

The present experimental study aims to explore the effect of an interactive smart toy on children's stress modulation during a stressful experience compared to a non-interactive prototype....

Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass

Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associat...

A Pharmacokinetic (PK) Study of ACH-0144471 Modified Release Prototype Formulations in Healthy Subjects

The purpose of this study is to evaluate and compare the plasma PK profiles of study drug, ACH-0144471, in healthy subjects after administration of a single dose of multiple ACH-0144471 pr...

The CYBERnetic LowEr Imb coGnitive Ortho-prostheis Plus Plus, 2nd Clinical Study (CLs++)

The aim of the project is to evaluate the efficacy of the Cyberlegs X-leg in people with a unilateral transfemoral (above the knee joint) and transtibial (under the knee joint) amputation....

PubMed Articles [937 Associated PubMed Articles listed on BioPortfolio]

Effects of operation conditions and suction pipeline parameters on flow characteristics and metering accuracy for selective catalytic reduction air-assisted urea dosing system.

Selective catalytic reduction is the main technology to reduce oxides of nitrogen of diesel exhaust. As an important part of the selective catalytic reduction system, the air-assisted urea dosing syst...

Risk factors for impaired wound healing and prolonged hospitalization in patients after amputation of the lower limb above the knee joint.

ntroduction: Lower limb amputation is a surgery performed as a last resort, when all other therapeutic options have been exhausted. The duration of treatment lasts from a few to several months and dep...

Risk factors for amputation are influenced by competing risk of death in patients with critical limb ischemia.

Patients with critical limb ischemia (CLI) have a high risk of amputation and death. Death is a competing risk that affects the estimated amputation risk. Our aim was to find the specific risk factors...

Amputation Following Burn Injury.

Amputation following burn injury is rare. Previous studies describe the risk of amputation after electrical burn injuries. Therefore, we describe the distribution of amputations and evaluate risk fact...

Amputation Versus Limb Reconstruction for Fibula Hemimelia: A Meta-Analysis.

Fibula hemimelia is the most common congenital deficiency of long bones. Primary treatment options include amputation with prosthetic fitting or limb reconstruction. The aim of our study was to conduc...

Medical and Biotech [MESH] Definitions

The part of a limb or tail following amputation that is proximal to the amputated section.

A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core component of the machinery for intracellular MEMBRANE FUSION. The sequence contains 2 SNARE domains, one is the prototype for the Qb-SNARES, and the other is the prototype for the Qc-SNARES.

Amputation or separation at a joint. (Dorland, 28th ed)

Amputation of a lower limb through the sacroiliac joint.

The removal of a limb or other appendage or outgrowth of the body. (Dorland, 28th ed)

More From BioPortfolio on "Hybrid Pump Technology"

Quick Search

Relevant Topic

Arthroplasty is a surgical procedure to restore the integrity and function of a joint. A joint can be restored by resurfacing the bones. An artificial joint (called a prosthesis) may also be used. Various types of arthritis may affect the joints. Osteo...

Searches Linking to this Trial