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Trial With UniCAR02-T Cells and Cluster of Differentiation (CD)123 Target Module (TM123) in Patients With Hematologic and Lymphatic Malignancies

2020-01-18 10:34:46 | BioPortfolio

Summary

This dose-escalating phase I trial assesses for the first time the safety, the side effects and the harmlessness, as well as the therapeutical benefit of the new study drug UniCAR02-T-CD123 in patients with hematologic and lymphatic malignancies positive for CD123 marker. The UniCAR02-T-CD123 drug is a combination of a cellular component (UniCAR02-T) with a recombinant antibody derivative (TM123) which together forms the active drug.

Study Design

Conditions

Acute Myeloid Leukemia (AML)

Intervention

Cyclophosphamide (Non-IMP), Fludarabine (Non-IMP), TM123 (IMP), UniCAR02-T (IMP)

Location

Universitätsklinikum Würzburg
Würzburg
Bayern
Germany
97080

Status

Recruiting

Source

Cellex Patient Treatment GmbH

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-01-18T10:34:46-0500

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