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2ccPA Study in Patients With Symptomatic Knee Osteoarthritis

2020-01-21 11:31:54 | BioPortfolio

Summary

This clinical trial is designed to determine safety and tolerability as well as the MTD of a single-dose 2ccPA and PK data in symptomatic knee OA.

Description

Osteoarthritis (OA) is a degenerative disease frequently associated with symptoms such as inflammation, stiffness, muscle weakness, joint swollen and joint pain. 2-carba-cyclic phosphatidic acid (2ccPA) is the derivative of natural occurring phospholipid mediator, cyclic phosphatidic acid (cPA). Previous studies suggested that 2ccPA inhibits inflammation and may relieve the pain caused by osteoarthritis.

This clinical study aims to assess the safety, tolerability, and pharmacokinetics as well as the maximal tolerated dose (MTD) of a single-dose 2ccPA in symptomatic knee OA. Safety and efficacy data for the design and conduction of subsequent studies will also be collected.

Study Design

Conditions

Osteoarthritis (OA) of the Knee

Intervention

2ccPA, placebo

Location

Veteran General Hospital Taipei
Taipei
Taiwan
112

Status

Recruiting

Source

Orient Europharma Co., Ltd.

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-01-21T11:31:54-0500

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