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Effects of RT234 on Exercise Parameters Accessed by CPET in Subjects With PAH

2020-02-16 17:40:47 | BioPortfolio

Summary

The objectives of this study are to evaluate the effects of RT234 on exercise parameters assessed by a specialized exercise test (Cardiopulmonary Exercise Test or CPET) in patients with pulmonary arterial hypertension (PAH).

Description

Consequences of pulmonary arterial hypertension are significant limitations in cardiorespiratory fitness (CRF), exercise capacity, as well as profound dyspnea with physical exertion. The objective of the present study is to assess the ability of a single inhaled dose of RT234 to acutely improve primary CPET measures of CRF and exercise capacity, and to lower the sensation of dyspnea with physical exertion compared to baseline CPET measures.

Study Design

Conditions

Pulmonary Arterial Hypertension

Intervention

Drug: RT234 - vardenafil inhalation powder; Device: Axially Oscillating Sphere dry powder inhaler (AOS DPI)

Location

Clinical Center of Serbia
Belgrade
Serbia
11000

Status

Not yet recruiting

Source

Respira Therapeutics, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-02-16T17:40:47-0500

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