Topic L. Reuteri in Children With Atopic Dermatitis

2020-02-16 17:40:50 | BioPortfolio


This study evaluate the safety and efficacy of L. reuteri vs placebo as an adjuvant for improve the skin appearence of children with mild or moderate atopic dermatitis. All children will receive the standar of care. Half of children will receive topical L. reuteri in cream, while the other half will receceive the standar of care + placebo


AD if a very frequent allergic skin disorders in children. Produce a negative significant impact on quality of life and related costs. Recently the changes of skin microbiota had been related with inadequate evolution of atopic dermatitis.

L. reuteri had been identified with some effect to reduce skin inflammation and help to modulate inflammatory pathways on skin. We expect using topical L. reuteri as adjuvant some improvement on skin appearance due to the mode of action previous referenced additionally to some potential changes on microbiome

Study Design


Atopic Dermatitis


Topical L. reeuteri


Hospital General Dr. Manuel Gea Gonzalez
Mexico city


Not yet recruiting


Innovacion y Desarrollo de Estrategias en Salud

Results (where available)

View Results


Published on BioPortfolio: 2020-02-16T17:40:50-0500

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Medical and Biotech [MESH] Definitions

A disseminated vesicular-pustular eruption caused by the herpes simplex virus (HERPESVIRUS HOMINIS), the VACCINIA VIRUS, or Varicella zoster (HERPESVIRUS 3, HUMAN). It is usually superimposed on a preexisting, inactive or active, atopic dermatitis (DERMATITIS, ATOPIC).

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Rare autosomal recessive disease with variable expressions. Clinical features of the disease include variable ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL; bamboo hair (trichorrhexis invaginata); and ATOPIC DERMATITIS. The disease is caused by mutations in the SPINK5 gene.

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