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Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

2020-02-19 18:28:44 | BioPortfolio

Summary

Investigators will evaluate and compare the efficacy of Sitagliptin/Metformin to metformin and sitagliptin on gdf9 and bmp15 gene expression on PCOS patients undergoing intracytoplasmic sperm injection(ICSI).

Description

This study was conducted in Infertility clinic of Mahdiyeh Educational Hospital, Tehran. Patients in the four groups receive the drug 2 months before the start of the ovulation cycle, and treatment will continue until the day of the oocyte aspiration. The drug provide by midwife to patients and both patient and physician blind to the treatment regimen. The participants randomly divide into four groups.The ovulation induction stimulate with GnRh antagonist.

Study Design

Conditions

Polycystic Ovary Syndrome

Intervention

placebo, metformin, Sitagliptin, Sitagliptin/metformin

Location

Mahdiyeh educational hospital
Tehran
Iran, Islamic Republic of
1989930002

Status

Recruiting

Source

Shahid Beheshti University of Medical Sciences

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-02-19T18:28:44-0500

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