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GPx Activity in Subjects With Aortic Stenosis Undergoing TAVR

2020-02-17 18:20:52 | BioPortfolio

Summary

The aim of this project is to investigate the association of glutathione peroxidase (GPx) and severe aortic stenosis (AS), as well as the impact of transcatheter aortic valve replacement (TAVR) on GPx activity post-procedure. The burden of oxidative stress will be determined by the measurement of GPx, superoxide dismutase (SOD) and lipoprotein A (Lp(a)). We hypothesize GPx activity is reduced in participants with severe AS vs control groups and GPx activity is to increase after TAVR is performed.

Study Design

Conditions

Glutathione Peroxidase Activity

Intervention

Blood draw to measure GPx activity, Blood draw to measure SOD activity, Blood draw to measure Lp(a) levels

Location

University of Florida
Jacksonville
Florida
United States
32209

Status

Not yet recruiting

Source

University of Florida

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-02-17T18:20:52-0500

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