GPx Activity in Subjects With Aortic Stenosis Undergoing TAVR

2020-02-17 18:20:52 | BioPortfolio


The aim of this project is to investigate the association of glutathione peroxidase (GPx) and severe aortic stenosis (AS), as well as the impact of transcatheter aortic valve replacement (TAVR) on GPx activity post-procedure. The burden of oxidative stress will be determined by the measurement of GPx, superoxide dismutase (SOD) and lipoprotein A (Lp(a)). We hypothesize GPx activity is reduced in participants with severe AS vs control groups and GPx activity is to increase after TAVR is performed.

Study Design


Glutathione Peroxidase Activity


Blood draw to measure GPx activity, Blood draw to measure SOD activity, Blood draw to measure Lp(a) levels


University of Florida
United States


Not yet recruiting


University of Florida

Results (where available)

View Results


Published on BioPortfolio: 2020-02-17T18:20:52-0500

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