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Vopratelimab (JTX-2011) Alone and in Combination With Anti-PD-1 or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid Tumors

2020-03-29 04:05:01 | BioPortfolio

Summary

JTX-2011-R01 is an open label, multicenter, rollover study that is designed to provide continued access to vopratelimab for eligible subjects with advanced solid tumor malignancies who have previously participated in a vopratelimab study (the parent study).

Description

Vopratelimab is an agonist monoclonal antibody that specifically binds to the Inducible CO-Stimulator of T cells (ICOS) to generate an anti-tumor immune response. This is an open label, roll over study to evaluate the long-term safety of continued treatment with vopratelimab monotherapy or combination treatment.

Study Design

Conditions

Cancer

Intervention

Vopratelimab, Ipilimumab, Nivolumab

Location

Washington University School of Medicine
Saint Louis
Missouri
United States
63110

Status

Recruiting

Source

Jounce Therapeutics, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-03-29T04:05:01-0400

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Medical and Biotech [MESH] Definitions

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