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Marfan syndrome is characterized by musculoskeletal manifestations, cardiovascular disease and ocular abnormalities, particularly ectopia lentis. Diagnosis depends on clinical evaluation, family history and molecular data: mutation in the fibrillin-1 gene (FBN1). Ectopia lentis is the most common ocular manifestation in Marfan syndrome with FBN1 mutation and is relatively specific to this disease when associated with other features. However, clinical examinations for identifying ectopia lentis have not really been codified. The purpose of this study is to describe a 5-grade classification of increasing severity for ectopia lentis based on clinical examination and to evaluate the predictive value for the early grades of ectopia lentis in order to help characterize this major clinical diagnosis criterion.
ophthalmological examinations using a slit lamp bio microscopy and a three-mirror lens, standard procedure.
Hopital Femme Mère Enfant
Hospices Civils de Lyon
Published on BioPortfolio: 2020-03-27T03:25:31-0400
Slit-lamp images are widely used in ophthalmology for the detection of cataract, keratopathy and other anterior segment disorders. In real-world practice, the quality of slit-lamp images c...
This study evaluates the safety and effectiveness of the Intelligent Retinal Implants System (IRIS V2). Blind patient suffering from Retinitis Pigmentosa, Cone Rod Dystrophy, or Choroidere...
Although epi-keratome laser-assisted in situ keratomileusis (Epi-LASIK), penetrating keratoplasty and pars plana vitrectomy with corneal epithelial debridement for diabetic retinopathy are...
The purpose of the evaluation is to confirm operability and usability of the SL-D301 Slit Lamp and the DC-4 digital camera attachment by conducting a usability evaluation and subsequently ...
Senile cataract is managed by cataract extraction and intra-ocular lens (IOL) implantation. The purpose of this study is to evaluate the safety and efficacy of the SeeLens AF, an acrylic h...
In this report, we highlight two effective and simple techniques of video documentation of the anterior chamber angle using the newer generation iPhone, iPhone11 Pro max. In these techniques, we also ...
To determine the vascular density of the anterior segment (AS) of the eye from the optical coherence tomography angiography (OCTA) images and slit-lamp photographs.
An 88-year-old woman with history of recent complicated pacemaker insertion presented with acute-onset malignant glaucoma recalcitrant to conservative medical therapy. Surgical intervention was discus...
To determine whether Demodex infestation in blepharitic patients can be confirmed by slit-lamp examination without the need for light microscopy.
We sought to demonstrate the feasibility of a lower-cost, portable method for qualitative and quantitative analysis of the corneal endothelium using a smartphone and slit-lamp biomicroscope.
A procedure that uses a SLIT LAMP to examine structures in the front of the EYE, such as the CONJUNCTIVA; CORNEA; IRIS; and AQUEOUS HUMOR.
A microscope with a light source that can be projected into a linear beam. It allows cross-sectional viewing of the AQUEOUS HUMOR; CONJUNCTEIVA; CORNEA; EYELIDS; IRIS; and lens (see LENS, EYE) of the eye.
Neurons that fire when an animal acts or observes the same action of another thus coding the motor response. They were originally discovered in the premotor and parietal cortex of the monkey and studies have shown that neurons that have a similar mechanism are present in humans. Mirror neurons are theorized to be related to social cognition.
Microscopy in which the samples are first stained immunocytochemically and then examined using an electron microscope. Immunoelectron microscopy is used extensively in diagnostic virology as part of very sensitive immunoassays.
Scanning microscopy in which a very sharp probe is employed in close proximity to a surface, exploiting a particular surface-related property. When this property is local topography, the method is atomic force microscopy (MICROSCOPY, ATOMIC FORCE), and when it is local conductivity, the method is scanning tunneling microscopy (MICROSCOPY, SCANNING TUNNELING).
Arthritis Fibromyalgia Gout Lupus Rheumatic Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Diction...
Cardiovascular disease (CVD)
Acute Coronary Syndromes (ACS) Blood Cardiovascular Dialysis Hypertension Stent Stroke Vascular Cardiovascular disease (CVD) includes all the diseases of the heart and circulation including coronary heart disease (angina...
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...