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Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)

2020-03-28 03:55:26 | BioPortfolio

Summary

To compare two evidence-based treatments, Cognitive Enhancement Therapy (CET) and Social Skills Training (SST) that have been shown in meta-analyses and in our own research to be effective to improve community functioning. The investigators will test the impact of CET and SST on community functioning, with special attention to their relative effectiveness for patients differing in baseline cognitive skills and age. The research uses a cluster design in which different mental health service centers are randomized to one of the two treatments.

Description

Aim 1. The investigators will test our hypothesis that CET will be associated with greater improvements than SST in both the primary outcome: community functioning (SAS, QLS), and the secondary outcomes of neuro- and social cognition (BACS and MSCEIT) and social skills (SSPA). . For study Aim 1,the investigators hypothesized that CET will be associated with greater improvements than SST in both the primary outcome: community functioning (SAS, QLS), and the secondary outcomes of neuro- and social cognition (NIH Toolbox and MSCEIT) and social skills (SSPA). Aim 2: The investigators will explore differential effectiveness of the two interventions by baseline cognitive functioning and age. For Aim 2, the investigators hypothesize that patients with less impairment in cognitive functioning at baseline will demonstrate relatively larger treatment gains in SST compared to those in CET than those who are initially more cognitively impaired, and that younger patients will benefit more from CET compared to those in SST than those who are older. The results of this study will address a key knowledge gap in the field and a decisional dilemma for clinicians.

Study Design

Conditions

Schizophrenia and Related Disorders

Intervention

Cognitive Enhancement Therapy, Social Skills Training

Location

Beth Israel Deaconess Medical Center
Boston
Massachusetts
United States
02215

Status

Not yet recruiting

Source

Beth Israel Deaconess Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-03-28T03:55:26-0400

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