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Multiple Doses of AT-1501-A201 in Adults With ALS

2020-03-31 04:03:56 | BioPortfolio

Summary

This is a Phase 2a, multi-center, open label, multiple dose study of AT-1501, a humanized monoclonal antibody antagonist to CD40LG. Approximately 54 adults with ALS will be enrolled into the study in the United States at up to 12 ALS treatment sites.

Participants will be enrolled into one of three ascending doses.

Description

This is a Phase 2a, multi-center, open label, multiple dose study of AT-1501, a humanized monoclonal antibody antagonist to CD40LG. Approximately 54 adults with ALS will be enrolled into the study in the United States at up to 12 ALS treatment sites.

Three ascending doses of AT-1501 will be administered as an IV infusion to sequentially enrolling cohorts. Each participant will receive 6 bi-weekly (every other week) infusions of AT-1501 over an 11-week period.

The study is estimated to take 19 weeks for participants.

Study Design

Conditions

Amyotrophic Lateral Sclerosis

Intervention

AT-1501

Status

Not yet recruiting

Source

Anelixis Therapeutics, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-03-31T04:03:56-0400

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