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Prescription Strategies of Amikacin in Intensive Care Patients on Renal Replacement Therapy: an Observational Prospective Multicenter Study

2020-03-29 04:04:43 | BioPortfolio

Summary

Amikacin is the aminoglycoside of choice for treatment of severe infections in intensive care. An achievement of its objectives in pharmacokinetics and pharmacodynamics is difficult in intensive care patients because of modification of their volume of distribution and renal clearance. Acute renal failure requiring renal replacement therapy is frequent in intensive care. Extrarenal purification modalities (continuous versus intermittent, type of dialysis membrane), which can influence amikacin clearance, are multiple and teams dependent. Guidelines of good practice for Amikacin in intensive care patients do not exist.

Description

The aim of this study is to describe strategies of prescription and monitoring of Amikacin in intensive care patients on renal replacement therapy.

Study Design

Conditions

Amikacin Treatment

Intervention

Data record

Location

Damien JOLLY
Reims
France

Status

Not yet recruiting

Source

CHU de Reims

Results (where available)

View Results

Links

Published on BioPortfolio: 2020-03-29T04:04:43-0400

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