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Argatroban for Preventing Occlusion and Restenosis After Intracranial and Extracranial Artery Stenting

2014-08-27 03:12:10 | BioPortfolio

Summary

The risk of restenosis post intracranial and extracranial artery stenting is 20-40%, therefore, in the past, aspirin and clopidogrel were performed as anticoagulant therapy post stenting.But this treatment had limited effectiveness upon restenosis. Argatroban is a selective thrombin inhibitor, and previous study had suggested that argatroban use post PCI could potentially prevent reocclusion. But there has no study on large sample of argatroban treated restenosis post cranial stenting. This study will test the safety and efficacy of the argatroban on prevent occlusion and restenosis in patients with intracranial and extracranial artery stenting.

Study Design

Allocation: Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

CVD

Intervention

Argatroban, non-argatroban treated group

Location

Department of Neurology, Jinling Hospital, Nanjing University School of Medicine
Nanjing
Jiangsu
China
210002

Status

Not yet recruiting

Source

Jinling Hospital, China

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:10-0400

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