Argatroban for Preventing Occlusion and Restenosis After Intracranial and Extracranial Artery Stenting

2014-08-27 03:12:10 | BioPortfolio


The risk of restenosis post intracranial and extracranial artery stenting is 20-40%, therefore, in the past, aspirin and clopidogrel were performed as anticoagulant therapy post stenting.But this treatment had limited effectiveness upon restenosis. Argatroban is a selective thrombin inhibitor, and previous study had suggested that argatroban use post PCI could potentially prevent reocclusion. But there has no study on large sample of argatroban treated restenosis post cranial stenting. This study will test the safety and efficacy of the argatroban on prevent occlusion and restenosis in patients with intracranial and extracranial artery stenting.

Study Design

Allocation: Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment




Argatroban, non-argatroban treated group


Department of Neurology, Jinling Hospital, Nanjing University School of Medicine


Not yet recruiting


Jinling Hospital, China

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:12:10-0400

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