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Oral Polypodium Leucotomos for Melasma

2014-08-27 03:12:11 | BioPortfolio

Summary

Primary Objective: To determine whether there is improvement in the melasma of participants taking oral Polypodium Leucotomos Secondary Objective: To determine whether oral Polypodium Leucotomos is well tolerated in study subjects with melasma.

To determine whether treatment with Polypodium Leucotomos improves the HRQoL

Description

Polypodium Leucotomos is a fern, also known as Calaguala used by the natives of northern Honduras as a treatment against malignant tumors Used in Spain and Central America for the treatment of psoriasis, atopic dermatitis and repigmentation of vitiligo.

Oral Polypodium Leucotomos is safe and effective in patients with melasma.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Conditions

Melasma

Intervention

Polypodium Leucotomos, Placebo

Location

University of Miami Cosmetic Center
Miami
Florida
United States
33140

Status

Completed

Source

University of Miami

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:11-0400

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Single-Blind Study Determining the Efficacy of Polypodium Leucotomos Extract Supplement in Decreasing Ultraviolet A (UVA) Premutagenic and Photoaging Markers

With this study we will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse effect...

Platelet Rich Plasma in Treatment of Melasma

Melasma is a common acquired disorder characterized by symmetric, hyperpigmented patches with an irregular outline, occurring most commonly on the face. The therapy for melasma has always ...

Prevalence of Serum-Vitamin D Abnormalities, Periodontitis and Anaemia in Patients With Melasma

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Melanil in the Treatment of Melasma

The purpose of the study is to assess the efficacy of Melanil facial cream in the treatment of melasma. The duration of this double-blind phase 3 clinical trial will be 54 weeks. The contr...

DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide.

BACKGROUND: Malar melasma has a chronic and recurrent character that may be related with epigenetic changes.

PubMed Articles [900 Associated PubMed Articles listed on BioPortfolio]

Double Blind, Placebo Controlled Evaluation of a Novel Skin Lightening Agent.

Melasma remains a troubling problem for physicans and patients alike. It is a chronic irregular, symmetric hyperpigmentation seen most often in women. In this study, a unique combination of ingredient...

Evaluation of the serum zinc level in adult patients with melasma: Is there a relationship with serum zinc deficiency and melasma?

Melasma is a common acquired hypermelanosis of sun-exposed skin, particularly on the face, which presents as symmetric, light- to gray-brown-colored macules and patches. There are several studies of s...

The clinicoaetiological, hormonal and histopathological characteristics of melasma in men.

Melasma is relatively uncommon in males, and there is a paucity of data on male melasma, including its clinical pattern, triggering factors, endocrine profile and histopathological findings.

Efficacy and safety of a novel picosecond laser using combination of 1 064 and 595 nm on patients with melasma: A prospective, randomized, multicenter, split-face, 2% hydroquinone cream-controlled clinical trial.

Melasma is a common acquired, chronic hypermelanosis and still remains a therapeutic challenge. The low-fluence 1 064 nm Q-switched Nd:YAG laser is the most widely used for the treatment of modera...

Oral Tranexamic Acid for the Treatment of Melasma: A Review.

Melasma is a common acquired disorder of hyperpigmentation that commonly affects those with skin of color. Tranexamic acid (TXA) is a novel treatment for melasma that has a multimodal mechanism of act...

Medical and Biotech [MESH] Definitions

A plant genus of the family POLYPODIACEAE. Members contain polypodoside.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

A plant genus of the family Pteridaceae. Members contain TRITERPENES. Some species in this genus are called maidenhair fern which is also a common name occasionally used for Lygodium (FERNS) and POLYPODIUM.

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

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