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Recovery Effect of Sugammadex Measured by Bispectral and Neurosense Indices

2014-08-27 03:12:16 | BioPortfolio

Summary

It has been demonstrated that antagonism of neuromuscular blockade (neostigmine 0.04 mg kg-1) affects depth of anaesthesia with an increase in bispectral index (mean maximal change of 7.1) and middle-latency auditory evoked potentials (mean maximal change of 9.7).

Sugammadex has a quicker and more complete effect than neostigmine. This study aims to demonstrate if sugammadex administration increases bispectral and neurosense indices of the depth of anesthesia while patients still receive propofol-remifentanil iv anesthesia.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Anesthesia

Intervention

Sugammadex - Nacl 9/00, Nacl 9/00 - sugammadex

Location

Hopital Foch
Suresnes
France
92151

Status

Not yet recruiting

Source

Hopital Foch

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:16-0400

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