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To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee

2014-08-27 03:12:17 | BioPortfolio

Summary

The study will determine whether the ability of canakinumab to inhibit IL-1β activity for sustained time-periods with a favorable impact on the three critical parameters of OA symptoms, namely 1) pain 2) function and 3) stiffness. These outcomes will be compared to placebo.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Osteoarthritis

Intervention

ACZ885, Placebo, Naproxen

Location

Pinnacle Research Group, LLC
Anniston
Alabama
United States
36207

Status

Recruiting

Source

Novartis

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:17-0400

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