Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses?

2014-08-27 03:12:18 | BioPortfolio


Seborrheic keratoses (SK's) are very common, but harmless skin lesions that commonly appear during adult life. Patients with seborrheic keratoses frequently desire treatment due to symptoms of itching and irritation or for cosmetic purposes. Seborrheic keratoses can be easily removed and have been treated in a number of different ways. Two of the simplest and most successful ways to remove seborrheic keratoses are cryosurgery and curettage.

The investigators are conducting this study to see which of these two treatments has the best result.

Approximately 24-30 people will take part in this research study at the Hershey Medical Center.

Study Design

Allocation: Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment


Seborrheic Keratosis


cryosurgery, Curettage


Penn State Milton S. Hershey Medical Center
United States




Milton S. Hershey Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:12:18-0400

Clinical Trials [175 Associated Clinical Trials listed on BioPortfolio]

PD P 506 A-PDT Versus Placebo-PDT and Cryosurgery for the Treatment of AK

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An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Seborrheic Keratoses

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Cryosurgery and Cream Combination for Actinic Keratosis

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A Randomized, Double-Blind, Vehicle-Controlled Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.

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PubMed Articles [88 Associated PubMed Articles listed on BioPortfolio]

Dermoscopy Improves the Diagnostic Accuracy of Melanomas Clinically Resembling Seborrheic Keratosis: Cross-Sectional Study of the Ability to Detect Seborrheic Keratosis-Like Melanomas by a Group of Dermatologists with Varying Degrees of Experience.

Malignant melanomas mimicking seborrheic keratosis (SK-like MMs) carry the risk of delayed diagnosis and inadequate treatment. The value of dermoscopy to improve the correct detection of these mimicke...

An ex-vivo evaluation of cytotoxicity and melanocyte viability after A-101 hydrogen peroxide topical solution 40% or cryosurgery treatment in Seborrheic Keratosis lesions.

Artemether for Topical Use in Patients with Seborrheic Keratosis.

Seborrheic Keratosis (SK) is the most common benign skin tumour. 80%-100% of people over 50 years are affected by SK and the diagnosis ranks among the 5 most common skin disorders seen by dermatologis...

Protoporphyrin IX formation after application of methyl aminolevulinate on the face and scalp with and without prior curettage.

Pulse photodynamic therapy (PDT) is carried out as classical PDT except that methyl aminolaevulinate (MAL) is removed after 30 min. Protoporphyrin IX (PpIX) accumulation becomes lower after 3 h in...

Nivolumab induced inflammation of seborrheic keratoses: a novel cutaneous manifestation in a metastatic melanoma patient.

Immune checkpoint inhibitors targeting the programmed cell death (PD)-1 receptor have dramatically changed the landscape of metastatic melanoma treatment. Nevertheless, these immuno-modulatory agents ...

Medical and Biotech [MESH] Definitions

Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.

A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS.

The use of freezing as a special surgical technique to destroy or excise tissue.

Any horny growth such as a wart or callus.

A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.

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