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A Phase I/IIa Study to Evaluate the Safety, Tolerability and Efficacy of Topical LTX-109 in Subjects Nasally Colonized With Methicillin-resistant Staphylococcus Aureus (MRSA)

2014-08-27 03:12:23 | BioPortfolio

Summary

This is i pilot study conducted to evaluate the safety, local tolerability and efficacy of LTX-109(Lytixar™), a lytic peptide designed to kill bacterias quickly and efficient. LTX-109 (Lytixar™)will be applied in the anterior nares in subjects who are carriers of nasal colonies of MRSA.

The extent of systemic absorption of LTX -109 when applied to the anterior nares will be evaluated and the effect of Lytixar™ as to clear colonies of MRSA during the the observation period and Week 2 to Week 9 after treatment.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator)

Conditions

Nasal Carriers of Methicillin-resistant Staphylococcus Aureus (MRSA)

Intervention

LTX-109

Location

Skåne University Hospital
Malmö
Sweden
205 02

Status

Recruiting

Source

Lytix Biopharma AS

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:23-0400

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