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Short course of palliative radiotherapy (5x5Gy)to the pelvis in patients with symptomatic rectal tumour with unresectable metastases may prevent palliative surgery with good palliative effect.The consolidating chemotherapy of Xelox may increase the efficacy of irradiation.
Patients with symptomatic rectal cancer and unresectable metastases receive to the pelvis 25 Gy in 5 fractions of 5 Gy over 5 days and Xelox consolidating chemotherapy after one week. Investigators arbitrarily assumed that palliative radiotherapy to the pelvis can replace the immediate surgery if at least 30% of patients would avoid delayed surgery until the end of their life, or for at least 18 months in the case of long-term survival.
Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
short course of palliative radiotherapy
M. Sklodowska-Curie Memorial Cancer Centre
Maria Sklodowska-Curie Memorial Cancer Center, Institute of Oncology
Published on BioPortfolio: 2014-07-23T21:08:32-0400
Radiotherapy (RT) is a potentially effective method in the treatment of symptoms of rectal carcinomas. Nevertheless, almost all the evidences about palliative RT in rectal cancer have been...
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Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Short-lived elementary particles found in cosmic radiation or produced from nuclear disintegration. Their mass is between that of protons and electrons and they can be negative, positive, or neutral. pi-Mesons (pions) are heavier than mu-mesons (muons) and are proposed for cancer radiotherapy because their capture and disintegration by matter produces powerful, but short-lived, secondary radiation.
Tumors or cancer of the RECTUM.
A nursing specialty concerned with care of patients facing serious or life-threatening illnesses. The goal of palliative nursing is to prevent and relieve suffering, and to support the best possible quality of life for patients and their families. Hospice nursing is palliative care for people in their final stages of life.
Physicians specializing in the treatment of cancer by RADIOTHERAPY.
Palliative care is the active holistic care of patients with advanced progressive illness. Management of pain and other symptoms and provision of psychological, social and spiritual support is paramount. The goal of palliative care is achievement of the ...
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...