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Procalcitonin as a Marker for the Length of Antibiotic Treatment in Peritonitis and Intra-abdominal Infections

2014-07-23 21:08:34 | BioPortfolio

Summary

Procalcitonin level used for determining length of antibiotic treatment in peritonitis and intra-abdominal infections. Hypothesis is that length of antibiotic use can be shortened by this method.

Description

Prospective randomized trial

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Secondary or Tertiary Peritonitis

Location

University Hospital of Lausanne
Lausanne
Switzerland
1011

Status

Recruiting

Source

University of Lausanne Hospitals

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:08:34-0400

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Medical and Biotech [MESH] Definitions

INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.

The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.

Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.

A medical facility which provides a high degree of subspecialty expertise for patients from centers where they received SECONDARY CARE.

An isomer of butanol that contains a tertiary butyl group that consists of three methyl groups, each separately attached to a central (tertiary) carbon.

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