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Long-term Bilateral Theta Burst Stimulation for the Treatment of Major Depression

2014-08-27 03:12:35 | BioPortfolio

Summary

Repetitive transcranial magnetic stimulation has been shown to be moderately effective in the treatment of major depression. Theta burst stimulation (TBS) is a new form of rTMS that may exert larger effects.

This sham-controlled study examines the effectivity of daily bilateral TBS to the dorsolateral frontal cortex over 6 weeks in 2x16 patients with major depression add on to the local standard of a combined pharmacological/psychotherapeutical treatment.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Major Depression

Intervention

Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation, TBS)

Location

University of Tübingen, Department of Psychiatry and Psychotherapy
Tübingen
Germany

Status

Recruiting

Source

University Hospital Tuebingen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:35-0400

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Medical and Biotech [MESH] Definitions

The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.

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A technique of brain electric stimulation therapy which uses constant, low current delivered via ELECTRODES placed on various locations on the scalp.

Stimulation of the brain, which is self-administered. The stimulation may result in negative or positive reinforcement.

Stimulation at an intensity below that where a differentiated response can be elicited.

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