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Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery

2014-08-27 03:12:43 | BioPortfolio

Summary

The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects. However, the analgesic effects of dexamethasone have not been adequately researched. Following surgery, patients are typically discharged home with PO opiates to manage post-operative pain. The investigators believe that by using Visual Analog scales for Pain the investigators can show that a single dose of dexamethasone can reduce pain scales and opiate consumption post-operatively, on POD 0 and POD 1 when compared to placebo.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Post Operative Pain

Intervention

Dexamethasone 8mg iv x1, placebo

Location

Beth Israel Deaconess Medical Center
Boston
Massachusetts
United States
02215

Status

Recruiting

Source

Beth Israel Deaconess Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:43-0400

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