Impact of Pre-surgical Nasal Bacterial Reduction on Postoperative Surgical Site Infections

2014-07-23 21:08:43 | BioPortfolio


Patients presenting in the Emergency Department or admitted to the hospital with displaced hip fractures who require hemiarthroplasty or open reduction internal fixation or with spinal instability/fractures in need of urgent surgical intervention will receive treatment to reduce the number of microorganisms in their nose prior to surgery. After surgery, the subjects will be observed for any surgical site infections.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention


Surgical Site Infection


3M Skin and Nasal Antiseptic


Sharp Memorial Hospital
San Diego
United States





Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:08:43-0400

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Medical and Biotech [MESH] Definitions

Infection occurring at the site of a surgical incision.

Surgical operations on the nose and nasal cavity.

Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)

Sterile clothing worn during surgical procedures to protect the surgical site from sources of contamination.

A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.

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