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A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee

2014-08-27 03:12:48 | BioPortfolio

Summary

PF-04191834 works in animal models by inhibiting one of the enzymes, 5-lipoxygenasein which is involved in the pathway that causes inflammation and pain. The purpose of this study is to test how effective, safe and tolerated PF-04191834 is in patients with osteoarthritis of the knee by itself or with naproxen, particularly to test if patients have less pain.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Osteoarthritis, Knee

Intervention

PF-04191834, PF-04191834 placebo, Naproxen placebo, PF-04191834 placebo, PF-04191834, Naproxen placebo, PF-04191834, Naproxen, PF-04191834 placebo, Naproxen, PF-04191834 placebo, PF-04191834

Status

Not yet recruiting

Source

Pfizer

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:48-0400

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