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Sunscreens in Patients With Cutaneous Lupus Erythematosus(CLE)

2014-08-27 03:12:49 | BioPortfolio

Summary

Part I: to investigate the efficacy of different sunscreens in the prevention of skin lesions following standardized photoprovocation with Ultraviolet A/Ultraviolet B (UVA/UVB) light in patients with CLE.

Part II: to evaluate the influence of different sunscreens on the expression of biomarkers in the skin of patients with CLE and of Healthy Controls following UV irradiation.

Description

Part I

Part I-interventions will be:

- Experimental intervention: Application of broad-spectrum sunscreens with a low, medium, and high Sun Protection Factor (SPF) in random order to uninvolved skin areas prior to standardized photoprovocation.

- Control intervention: Intra-individual application of vehicle in random order; standardized photoprovocation of vehicle treated and untreated areas.

Part II

Part II-interventions will be:

- Experimental intervention: Application of a broad-spectrum sunscreen with a high SPF to uninvolved skin areas prior to UV irradiation.

- Control intervention: UV irradiation of untreated areas.

Study Design

Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Cutaneous Lupus Erythematosus

Intervention

Daylong products

Location

Klinik und Poliklinik für Hautkrankheiten, Universitätsklinikum Münster
Münster
Germany
48149

Status

Recruiting

Source

Spirig Pharma Ltd.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:49-0400

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