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Published on BioPortfolio: 2014-10-03T16:35:43-0400
The two co-primary objectives of this study are to assess in Japanese patients with severe sepsis and/or septic shock: 1) the safety and tolerability of two different doses of intravenous ...
This is a double-blind, placebo-controlled, multi-center, dose-escalation study to assess the safety, tolerability, PK and PD of single and multiple ascending intravenous infusions of Cyto...
A sepsis early warning predictive algorithm, InSight, has been developed and validated on a large, diverse patient cohort. In this prospective study, the ability of InSight to predict seve...
In this prospective study, the ability of a machine learning algorithm to predict sepsis and influence clinical outcomes, will be investigated at Cabell Huntington Hospital (CHH).
The purpose of this study is to determine whether BMS-936559 is safe and has the desired pharmacologic activity in patients who have severe sepsis.
To evaluate the effect of probiotics on cytokines in children with severe sepsis.
Case fatality in pregnancy-associated severe sepsis or septic shock appears reduced compared with nonpregnant women with severe sepsis or septic shock. It remains unclear if this difference is due to ...
This study was performed to evaluate the association of monocyte counts with mortality, the rate of bacteremia and organ dysfunction and to evaluate whether the change in monocyte counts from the prem...
Globally, sepsis is a major cause of mortality through the combination of cardiovascular collapse and multi-organ dysfunction. Pregnancy appears to increase the risk of death in sepsis, but the exact ...
Angiopoietins are postulated diagnostic biomarkers in children and adults with severe sepsis and septic shock. The diagnostic value of angiopoietins in children less than 5 years old has not been esta...
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Acute neurological dysfunction during severe SEPSIS in the absence of direct brain infection characterized by systemic inflammation and BLOOD BRAIN BARRIER perturbation.
The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.
Blood infection that occurs in an infant younger than 90 days old. Early-onset sepsis is seen in the first week of life and most often appears within 24 hours of birth. Late-onset occurs after 1 week and before 3 months of age.
Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.