This study is looking at the advantage of establishing surgical drainage for Crohn's fistulas and abscesses prior to starting medical therapy.
Currently the importance of surgically established drainage of Crohn's perianal fistulas prior to medical therapy is controversial. Several retrospective studies have suggested a benefit to this approach. (1, 2) However, there have been no prospective studies performed to answer this important question. This study aims to definitively answer this question. Our hypothesis is that by establishing surgical drainage of all perianal fistulas and abscesses prior to initiation of medical therapy, further abscess formation will be prevented and the rate of durable fistula healing will improve.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Crohns Disease
Surgically established drainage of perianal fistulas &/or abscesses BEFORE medical tx
Vanderbilt University Medical Center
Nashville
Tennessee
United States
37232-1375
Not yet recruiting
Vanderbilt University
Published on BioPortfolio: 2014-08-27T03:12:50-0400
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Devices, usually incorporating unidirectional valves, which are surgically inserted in the sclera to maintain normal intraocular pressure.
Surgically-created Structures
Organs or parts of organs surgically formed from nearby tissue to function as substitutes for diseased or surgically removed tissue.
Hidradenitis Suppurativa
A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.
Medical Savings Accounts
Tax-exempt trusts or custodial accounts established by individuals with financial institutions for saving money for future medical expenses.
Fee Schedules
A listing of established professional service charges, for specified dental and medical procedures.