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Efficacy and Safety of Bovine Intestinal Alkaline Phosphatase (bIAP) During Heart Surgery

2014-08-27 03:12:54 | BioPortfolio

Summary

This multi-centre prospective, randomised, double-blind, placebo-controlled study is designed to evaluate the efficacy and safety of bovine intestinal alkaline phosphatase (bIAP) in reducing the pro-inflammatory post-surgical responses and thereby preserving organ functions in patients undergoing invasive cardiac surgery: combined aortic valve replacement and coronary artery bypass grafting.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Inflammation

Intervention

bIAP bolus and 8h infusion, placebo bolus and 8h infusion

Location

Catharina Ziekenhuis, Dept. CardioThoracic Surgery
Eindhoven
Netherlands
5623 EJ

Status

Recruiting

Source

Alloksys Life Sciences B.V.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:54-0400

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