Continuous Femoral Nerve Blocks: Relative Effects of Basal Infusion and Bolus Doses on Sensory and Motor Function

2014-08-27 03:12:54 | BioPortfolio


This is a research study to determine if the way local anesthetic- or numbing medication- is delivered through a tiny tube next to the nerves that go to the thigh affects the strength and sensation in the thigh.


Specific Aim: Researc study to test the null hypothesis that differing the delivery method (continuous basal infusion vs. repeated bolus doses) but providing an equal total dose of Ropivacaine has no impact on quadriceps muscle strength. These results will help define the optimal delivery method of local anesthetic used for continuou peripheral nerve blocks and help guide future research in this clinically relevant area.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Nerve Block


Continuous Infusion, Bolus Administered


UCSD Medical Center, Hillcrest
San Diego
United States


Enrolling by invitation


University of California, San Diego

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:12:54-0400

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