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Transcranial Direct Stimulation in Chronic Pelvic Pain

2014-08-27 03:12:55 | BioPortfolio

Summary

The purpose of this study is to determine whether transcranial direct current stimulation (tDCS) is effective in reducing pain in subjects with chronic pelvic pain. Our hypothesis is that tDCS will decrease pain significantly when compared to sham stimulation.

In addition, the investigators aim to determine the safety of this intervention via a battery of neurocognitive tests. The investigators hypothesize that tDCS induces no cognitive worsening as compared with sham tDCS.

Description

Subjects will receive 4 weeks of stimulation on consecutive days (Monday- Friday).

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Pelvic Pain

Intervention

Transcranial Direct Current Stimulation

Location

Spaulding Rehabilitation Hospital
Boston
Massachusetts
United States
02114

Status

Recruiting

Source

Spaulding Rehabilitation Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:55-0400

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PubMed Articles [18092 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

A technique of brain electric stimulation therapy which uses constant, low current delivered via ELECTRODES placed on various locations on the scalp.

Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.

The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.

Pain in the pelvic region of genital and non-genital origin and of organic or psychogenic etiology. Frequent causes of pain are distension or contraction of hollow viscera, rapid stretching of the capsule of a solid organ, chemical irritation, tissue ischemia, and neuritis secondary to inflammatory, neoplastic, or fibrotic processes in adjacent organs. (Kase, Weingold & Gershenson: Principles and Practice of Clinical Gynecology, 2d ed, pp479-508)

Measurable changes in activities in the CEREBRAL CORTEX upon a stimulation. A change in cortical excitability as measured by various techniques (e.g., TRANSCRANIAL MAGNETIC STIMULATION) is associated with brain disorders.

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