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Electromyographic (EMG) on the Anaesthesia Monitor

2014-08-27 03:12:57 | BioPortfolio

Summary

Intubation may induce electromyographic (EMG) activity, causing depth of anaesthesia monitors to show misleadingly high values. The investigators want to investigate whether this EMG activity can be visually seen on the anaesthesia monitor.

Description

Patients are anaesthetized with target controlled infusion of propofol. To facilitate intubation, the patients are randomized to receive rocuronium either 0,6 mg/kg or 1,2 mg/kg. BIS, Entropy and the biosignal collected with the Entropy strip are collected on a computer. The visible biosignal on the anaesthesia monitor is recorded with a video camera. BIS, Entropy, biosignal and video clip of the anaesthesia monitor will be analyzed in detail.

Study Design

Allocation: Randomized, Control: Dose Comparison, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Anaesthesia

Intervention

Rocuronium bromide, Rocuronium bromide

Location

Tampere University Hospital
Tampere
Finland

Status

Completed

Source

Tampere University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:12:57-0400

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The duration of rocuronium in patients with BMI more than 30 kg m is prolonged. Whether the reverse is true when BMI is less than 18.5 kg m is unclear.

Anaphylactic shock after sugammadex administration, induced by formation of a sugammadex-rocuronium complex.

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Medical and Biotech [MESH] Definitions

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Antimuscarinic quaternary ammonium derivative of scopolamine used to treat cramps in gastrointestinal, urinary, uterine, and biliary tracts, and to facilitate radiologic visualization of the gastrointestinal tract.

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