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Hypothesis; That inhibition of plasma Blys by the monoclonal antibody Belimumab will reduce both the survival of the lymphoplasmacytoid cells of Waldenstrom Macroglobulinaemia (WM), and their production of monoclonal IgM, resulting in a reduction of IgM paraprotein.
Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Symptomatic Waldenstroms Macroglobulinaemia
The Peter MacCallum Cancer Centre
Cancer Trials Australia
Published on BioPortfolio: 2014-08-27T03:13:01-0400
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An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
The amount time between exposure to an infectious agent and becoming symptomatic.
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