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A Study of Belimumab in Treating Symptomatic Waldenstroms Macroglobulinaemia

2014-08-27 03:13:01 | BioPortfolio

Summary

Hypothesis; That inhibition of plasma Blys by the monoclonal antibody Belimumab will reduce both the survival of the lymphoplasmacytoid cells of Waldenstrom Macroglobulinaemia (WM), and their production of monoclonal IgM, resulting in a reduction of IgM paraprotein.

Study Design

Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Symptomatic Waldenstroms Macroglobulinaemia

Intervention

Belimumab

Location

The Peter MacCallum Cancer Centre
Melbourne
Victoria
Australia
3002

Status

Recruiting

Source

Cancer Trials Australia

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:01-0400

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Successful sequential therapy with rituximab and belimumab in patients with active systemic lupus erythematosus: a case series.

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