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Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration

2014-08-27 03:13:14 | BioPortfolio

Summary

Adalimumab is a humanized recombinant monoclonal antibody fragment targeted against tumor necrosis factor. This study will assess the safety and efficacy of intravitreal adalimumab administered in patients with choroidal neovascularization secondary to age-related macular degeneration non-responders to the conventional treatment with intravitreal ranibizumab.

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Age-Related Macular Degeneration

Intervention

Adalimumab

Location

Servicio de Oftalmologia. Hospital Universitario Vall d'Hebron
Barcelona
Spain
08035

Status

Recruiting

Source

Hospital Universitari Vall d'Hebron Research Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:14-0400

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Medical and Biotech [MESH] Definitions

A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.

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