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Functional Magnetic Resonance Imaging (MRI) of Hypnosis and Mindfulness Meditation

2014-08-27 03:13:14 | BioPortfolio

Summary

Hypnotic trance and mindfulness meditation have both been shown to have benefits for physical health. The current study seeks to determine if there are distinct patterns of brain activity that correlate with hypnotic trance, mindfulness meditation or both, and to relate these patterns to measurable markers of physical well-being. Precise neuroimaging of heightened attentional states will guide future researchers and practitioners toward more effective techniques of mind/body control.

Description

Our goal is to determine the functional brain networks that define and distinguish two induced states of sustained attention -- hypnosis and mindfulness -- that may be of substantial relevance to medicine.

Defining the neural underpinnings of these states would have broad implications for understanding how cognitive states emerge from functional networks, how they affect peripheral autonomic nervous system activity, and how their therapeutic efficacy can be optimized.

We propose a functional MRI study using resting state methodology to study 20-40 subjects from each of the four following groups:

1. Highly hypnotizable subjects

2. Minimally hypnotizable subjects

3. Experienced mindfulness meditators

4. Novice mindfulness meditators. The ability to be hypnotized is a stable and measurable trait that can be pre-screened and quantified. Dr. Spiegel will select subjects according to their ability to be hypnotized prior to the MRI visit (see ?recruiting? below). We will seek greatest contrast between groups by enrolling those with the highest (8-10) and lowest (0-2) scores on the Hypnotic Induction Profile. The presence of a poorly hypnotizable group allows for a control condition of those who have undergone an identical induction routine without achieving hypnotic trance. Similarly, novice meditators will serve as a control for the group experienced in mindfulness meditation.

Prior studies have shown differences in both brain activation and grey matter volume associated with longer practice of meditation (> 4 years) compared with novice meditators. As such, experienced meditators will be defined as those with a regular meditation practice of four years or longer. Novice meditators will be new practitioners who are interested in mindfulness meditation practice, and who completed a one-hour meditation training during the week before their study participation.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Conditions

HYPNOSIS

Intervention

Hypnosis, Meditation

Location

Stanford University School of Medicine
Stanford
California
United States
94305

Status

Recruiting

Source

Stanford University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:14-0400

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Antenatal hypnosis is associated with a reduced need for pharmacological interventions during childbirth. This trial seeks to determine the efficacy or otherwise of antenatal group hypnosi...

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Meditation and Hypnosis for Chronic Depressed Mood

This study examined whether meditation or group psychotherapy including hypnosis plus education, compared to an educational control, would ameliorate long-term depressed mood.

Hemodynamic Correlates of Distinct Hypnotic States

The investigation will assess the brain activation connectivity patterns associated with hypnosis and possible hypnotic sub-states by means of functional magnetic resonance imaging (fMRI)....

Evaluation of Medical and Economic Incidence of Hypnosis

Hypnosis in conization is more and more use to substitute General Anesthesia (GA) in Anesthesia's field. This study wants to prove that the Hypnosis in conization are cheaper.

PubMed Articles [94 Associated PubMed Articles listed on BioPortfolio]

Hypnosis and Psychoanalysis: Toward Undoing Freud's Primal Category Mistake.

Hypnosis predates psychoanalysis, when autohypnotic pathologies were identified through the lens of hypnosis, and labeled "hypnoid hysteria" in the language of the day. The broad spectrum of disorders...

Hypnosis: A Psychodynamic Perspective.

The relationship between hypnosis and psychoanalysis has always been complex, and often acrimonious. When Freud abandoned hypnosis as both the foundation of his theory building and his clinical interv...

EFFECTS OF CONVERSATIONAL HYPNOSIS ON RELATIVE PARASYMPATHETIC TONE AND PATIENT COMFORT DURING AXILLARY BRACHIAL PLEXUS BLOCKS FOR AMBULATORY UPPER LIMB SURGERY:A Quasiexperimental Pilot Study.

This two-center quasiexperimental pilot study was to determine the effect of conversational hypnosis on patient comfort and parasympathetic tone, which may represent a quantitative measure of hypnotic...

Reconsidering Hypnosis and Psychoanalysis: Toward Creating a Context for Understanding.

Sigmund Freud developed what became psychoanalysis in the context of his experiences with hypnosis and the treatment of the grand hysterics of his era, conditions largely classified among the dissocia...

The efficacy of hypnosis on pain, wound healing, anxiety and stress in children with acute burn injuries: a randomized controlled trial.

No randomized controlled trial (RCT) has investigated the efficacy of hypnosis for reducing pain and improving healing in children with burns. This RCT aimed to investigate whether hypnosis decreases ...

Medical and Biotech [MESH] Definitions

A state of increased receptivity to suggestion and direction, initially induced by the influence of another person.

Process in which a patient is induced into a trance-like state in order to relieve anxiety during a dental procedure.

Procedure in which an individual is induced into a trance-like state to relieve pain. This procedure is frequently performed with local but not general ANESTHESIA.

A state of consciousness in which the individual eliminates environmental stimuli from awareness so that the mind can focus on a single thing, producing a state of relaxation and relief from stress. A wide variety of techniques are used to clear the mind of stressful outside interferences. It includes meditation therapy. (Mosby's Medical, Nursing, and Allied Health Dictionary, 4th ed)

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor analgesic and muscle relaxant properties. Small doses have been shown to be anti-analgesic and lower the pain threshold. (From Martindale, The Extra Pharmacopoeia, 30th ed, p920)

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