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Bioequivalence Study of Generic Tretinoin 0.1% Microsphere Gel, 0.1% Retin-A Micro® and Placebo

2014-10-23 21:11:39 | BioPortfolio

Published on BioPortfolio: 2014-10-23T21:11:39-0400

Clinical Trials [382 Associated Clinical Trials listed on BioPortfolio]

To Evaluate the Therapeutic Equivalence and Safety of TRETINOIN CREAM, 0.05% and RLD in the Treatment of Acne Vulgaris

Bioequivalence study comparing Tretinoin Cream, 0.05% to RETIN-A®.

Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin

The use of topical retinoids is a mainstay and basis of early acne treatment to prevent the progression to inflammatory lesions. Post oral isotretinoin, it is not uncommon for non-inflamm...

To Evaluate the Therapeutic Equivalence and Safety of TRETINOIN CREAM, 0.1% and RLD in the Treatment of Acne Vulgaris

Bioequivalence study comparing Tretinoin Cream, 0.1% to RETIN-A®.

Safety and Efficacy Study of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel to Treat Rosacea

The purpose of this study is to determine whether Clindamycin Phosphate 1.2% And Tretinoin 0.025% Gel are effective and safe in the treatment of papulopustular rosacea.

Tretinoin and Interleukin-2 in Treating Patients With Stage IV Kidney Cancer

RATIONALE: Tretinoin may help cells that are involved in the body's immune response to work better. Interleukin-2 may stimulate the white blood cells to kill kidney cancer cells. Giving tr...

PubMed Articles [2451 Associated PubMed Articles listed on BioPortfolio]

Tretinoin (0.05% cream versus 5% peel) for photoaging and field cancerization of the forearms: randomized, evaluator-blinded, clinical trial.

Topical tretinoin cream is the gold standard treatment for skin aging, particularly photoaging. The purpose of tretinoin peel is to obtain similar results but in a shorter time, however there have bee...

Self-assembly three-dimensional optical devices: from microsphere to microlens array.

We report rapid formation of three-dimensional micro optical devices by silica nanoparticle self-assembly in a face-centered cubic (fcc) structure. By controlling the hydrophobic interactions, the sel...

Tretinoin Loaded Nanoemulsion for Acne Vulgaris: Fabrication, Physicochemical and Clinical Efficacy Assessments.

Acne vulgaris is a common inflammatory skin condition which is treated using Tretinoin (TRE), a widely used retinoid. Nano emulations (NEs) are colloidal nano-sized particles that enhance the therapeu...

In-fiber whispering-gallery mode microsphere resonator-based integrated device.

A novel in-fiber whispering-gallery mode (WGM) microsphere resonator-based integrated device is reported. It is fabricated by placing a silica microsphere into an embedded dual-core hollow fiber (EDCH...

Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study.

Intra-articular corticosteroids relieve osteoarthritis pain, but rapid systemic absorption limits efficacy. FX006, a novel, microsphere-based, extended-release triamcinolone acetonide (TA) formulation...

Medical and Biotech [MESH] Definitions

An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. The three most prominent theories used to explain the etiology of the disease are that acids produced by bacteria lead to decalcification; that micro-organisms destroy the enamel protein; or that keratolytic micro-organisms produce chelates that lead to decalcification.

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

Any normal or abnormal coloring matter in PLANTS; ANIMALS or micro-organisms.

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