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Non Surgical Management for Uterine Residua After Pregnancy Termination, Abortion or Delivery

2014-08-27 03:13:15 | BioPortfolio

Summary

The aim of the study is to find out whether conservative treatment - expectant management or medical therapy using misoprostol is beneficial in the case of uterine residua, and which treatment is better.

Description

Retained products of conception are estimated to occur after approximately 1-6% of pregnancies, probably more often after termination of early pregnancies then after term pregnancy. Complication are abdominal pain, infection, bleeding and for the long term - intrauterine adhesions.Blood clots in the uterine cavity can cause similar complications. The definitive treatment is curettage or hysteroscopy, both of which are carried out under general anesthesia and require an operating theater. Although expectant management and uterotonic drugs are practically used in such situation, they are not described in the literature.This study compare between the outcome of misoprostol treatment and expectant management in the case of intrauterine residua after completion of pregnancy.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Intra-uterine Residua

Intervention

misoprostol

Location

HaEmek medical center
Afula
Israel

Status

Not yet recruiting

Source

HaEmek Medical Center, Israel

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:15-0400

Clinical Trials [796 Associated Clinical Trials listed on BioPortfolio]

Dry vs Wet Misoprostol for Cervical Dilation in First Trimester Abortion

This study aims to verify whether the moisture of 400 µg of misoprostol pre uterine evacuation increases the dilatation of uterine cervix compared to dry misoprostol

Misoprostol Prior to Intra-Uterine Device (IUD) Insertion in Nulliparous Women

The purpose of this study is to see if inserting misoprostol in the vagina or between your cheek and gum before inserting an IUD in a woman who has never had a baby makes it easier and les...

Use of an Intra Uterine Balloon to Prevent Recurrent Adhesions

Patients suffering of subfertility as a consequence of intra uterine adhesions could be treated with adhesiolysis by hysteroscopy. Post-operative recurrent adhesions could be developed. To...

the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation : RCT

assess the effect of using misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications. Research question Does pre-operativ...

Diffusion-weighted Cerebral MRI and Intra Uterine Growth Restriction.

The purpose of this study is to compare the apparent diffusion coefficient in the frontal lobe of foetuses with intra-uterine growth restriction and poor neonatal outcome compared with foe...

PubMed Articles [2009 Associated PubMed Articles listed on BioPortfolio]

Mifepristone Pretreatment for the Medical Management of Early Pregnancy Loss.

Medical management of early pregnancy loss is an alternative to uterine aspiration, but standard medical treatment with misoprostol commonly results in treatment failure. We compared the efficacy and ...

Induction of Labor Using One Dose versus Multiple Doses of Misoprostol - A Randomized Controlled Trial.

Misoprostol is a common agent used to ripen the cervix and induce labor, yet there is no clear evidence of the optimal number of doses needed to achieve a higher rate of vaginal delivery.

The costs and cost effectiveness of providing second-trimester medical and surgical safe abortion services in Western Cape Province, South Africa.

In South Africa, access to second-trimester abortion services, which are generally performed using medical induction with misoprostol alone, is challenging for many women. We aimed to estimate the cos...

Uterine and ovary blood flow after uterine desarterialization

The aim of this article is to compare the effect of uterine desarterialization (UD) and hypogastric arteries ligature (HAL) in uterine and ovarian blood flow indirectly measured with the pulsatility i...

The Detection of Uterine Leiomyoma (Fibroid) Calcifications on 18F-NaF PET/CT.

Uterine leiomyomas (fibroids) are the most common type of uterine neoplasms in premenopausal women. Leiomyomas are estrogen dependent and tend to atrophy and shrink in size after menopause. Dystrophic...

Medical and Biotech [MESH] Definitions

Inflation of a balloon catheter within the uterine cavity to control UTERINE HEMORRHAGE.

Measurement or recording of contraction activity of the uterine muscle. It is used to determine progress of LABOR, OBSTETRIC and assess status of pregnancy. It is also used in conjunction with FETAL MONITORING to determine fetal response to stress of maternal uterine contractions.

Pathological processes of the UTERINE CERVIX.

Tumors or cancer of the UTERINE CERVIX.

Loss or destruction of the epithelial lining of the UTERINE CERVIX.

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